2017年5月9日星期二

Prohormones


by Alen Hao –Sales Manager of HGH ,Email:alen@ok-biotech.com

(Note: Prohormones Are Now Illegal and Classified as Anabolic Steroids as of Dec. 18th, 2014)


Prohormones are powerful anabolic compounds that have been the subject of debate and controversy for many years. The prohormone market first gained steam in the late 1990’s, largely thanks to individuals such as chemist Patrick Arnold and the media hysteria surrounding Mark McGwire’s bottle of Andro (androstendione). Although originally legal, prohormones have seen numerous roadblocks, and manufactures have discovered many loopholes and gray areas of the law. Such loopholes have kept these anabolic supplements on the shelves at every retailer; that is until now. In early December of 2014, the United States Congress dealt its final blow to the prohormone market effectively making any and all current and future prohormones or designer steroids illegal for sale or purchase.

What are Prohormones?
Prohormones are anabolic androgenic steroid precursors. In short, these substances are not anabolic steroids, but once ingested convert to produce an anabolic steroid action. However, while this is the purpose of a prohormone, some supplements that carry the prohormone label have been nothing but an anabolic steroid that requires no conversion. The popular Superdrol is perhaps the best example of a steroid being labeled a prohormone.

Because prohormones were not part of the Steroid Control Act of 1990, many athletes and bodybuilders have opted for the legal route in order to stay within the safety of the law. And prohormones work, they can work very well. Rarely will a prohormone have as strong as an effect as a true anabolic steroid, but because of the legal comfort provided, they proved to be a suitable choice for many men. However, with the passage of the 2014 Designer Anabolic Steroid Control Act of 2014 (HR 4771), this comfort zone no longer exists. Sale or purchase of prohormones in the United States will result in fines and/or jail time

Deca 200

The End of Prohormones:
In 2004, the U.S. congress enhanced the already strict Steroid Control Act of 1990 with the Steroid Control Act of 2004. The 2004 legislation stiffened the already stringent steroid laws, but it was its accompanying prohormone legislation that was its largest accomplishment. Numerous hormones and precursors were added to the Controlled Substance list; however, this ban proved to be weak in the end. Each and every year, supplement manufactures would alter their compounds. One could take a banned precursor and alter it slightly, thereby creating a new and legal substance. In time, such substances would find themselves on the banned list as well, but as soon as they did a new one was around the corner.

Enter the 2014 Designer Anabolic Steroid Control Act of 2014 – the updated legislation signed by President Obama and unanimously passed by congress has effectively closed all loopholes left open by the 2004 Act. No longer is enforcement of prohormone law in the hands of the FDA, but HR 4771 has given all authority to the DEA. The new legislation adds twenty-five (25) compounds to the Controlled Substance list, but more importantly makes it impossible for new substances or compounds to be created.

Originally, when a substance came under fire it was up to the FDA to prove that the accused substance carried or created anabolic steroid like action. The new law now puts the burden of proof on the manufacture. The U.S. Justice department has been given the power to add any substance to the list at any time, and it is up to the manufacture to prove it is not an anabolic substance. This is a nearly impossible for any manufacturer of prohormones as the law states “a drug or hormonal substance (other than estrogens, progestins, corticosteroids, and dehydroepiandrosterone)…derived from, or has a chemical structure substantially similar to, 1 or more anabolic steroids listed in (the new list of banned substances in Appendix 1) shall be considered to be an anabolic steroid for the purpose of this Act.” In simpler terms, the past legislation required that the substance carry a similar chemical relation to testosterone, and then it had to be proven to be anabolic. HR 4771 only requires that the substance be chemically related, even a slight relation is enough to see it banned and the manufacturer and retailer jailed. The DEA does not have to prove the substance is anabolic.

Violators of HR 4771 face some of the harshest penalties seen in the war on steroids:
Manufacturers & Distributors: $500,000 fine per violation
Retailers: $1,000 fine per violation
“(C) In the case of a violation of paragraph (16) of subsection (a) of this section by an importer, exporter, manufacturer, or distributor (other than as provided in subparagraph (D)), up to $500,000 per violation. For purposes of this subparagraph, a violation is defined as each instance of importation, exportation, manufacturing, distribution, or possession with intent to manufacture or distribute, in violation of paragraph (16) of subsection (a).” – Sec. 3 - subsection (c)(1)(C)

“(D) In the case of a distribution, dispensing, or possession with intent to distribute or dispense in violation of paragraph (16) of subsection (a) of this section at the retail level, up to $1000 per violation. For purposes of this paragraph, the term at the retail level refers to products sold, or held for sale, directly to the consumer for personal use. Each package, container or other separate unit containing an anabolic steroid that is distributed, dispensed, or possessed with intent to distribute or dispense at the retail level in violation of such paragraph (16) of subsection (a) shall be considered a separate violation.” – Sec. 3 – subsection (c)(1)(D)

Full List of Substances Added by HR 4771

• (l) 5α-Androstan-3,6,17-trione;
• (li) 6-bromo-androstan-3,17-dione;
• (lii) 6-bromo-androsta-1,4-diene-3,17-dione;
• (liii) 4-chloro-17α-methyl-androsta-1,4-diene-3,17β-diol;
• (liv) 4-chloro-17α-methyl-androst-4-ene-3β,17β-diol;
• (lv) 4-chloro-17α-methyl-17β-hydroxy-androst-4-en-3-one;
• (lvi) 4-chloro-17α-methyl-17β-hydroxy-androst-4-ene-3,11-dione;
• (lvii) 4-chloro-17α-methyl-androsta-1,4-diene-3,17β-diol;
• (lviii) 2α,17α-dimethyl-17β-hydroxy-5α-androstan-3-one;
• (lix) 2α,17α-dimethyl-17β-hydroxy-5β-androstan-3-one;
• (lx) 2α,3α-epithio-17α-methyl-5α-androstan-17β-ol;
• (lxi) [3,2-c]-furazan-5α-androstan-17β-ol;
• (lxii) 3β-hydroxy-estra-4,9,11-trien-17-one;
• (lxiii) 17α-methyl-androst-2-ene-3,17β-diol;
• (lxiv) 17α-methyl-androsta-1,4-diene-3,17β-diol;
• (lxv) Estra-4,9,11-triene-3,17-dione;
• (lxvi) 18a-Homo-3-hydroxy-estra-2,5(10)-dien-17-one;
• (lxvii) 6α-Methyl-androst-4-ene-3,17-dione;
• (lxviii) 17α-Methyl-androstan-3-hydroxyimine-17β-ol;
• (lxix) 17α-Methyl-5α-androstan-17β-ol;
• (lxx) 17β-Hydroxy-androstano[2,3-d]isoxazole;
• (lxxi) 17β-Hydroxy-androstano[3,2-c]isoxazole;
• (lxxii) 4-Hydroxy-androst-4-ene-3,17-dione[3,2-c]pyrazole-5α-androstan-17β-ol;
• (lxxiii) [3,2-c]pyrazole-androst-4-en-17β-ol;
• (lxxiv) [3,2-c]pyrazole-5α-androstan-17β-ol;

All Current Banned Prohormones:

• 5α-Androstan-3,6,17-trione
• (A saturated/’5a-reduced’ form of 6-oxo)
• 6-bromo-androstan-3,17-dione
• (A saturated form of the aromatase inhibitor 6-bromoandrostenedione)
• 6-bromo-androsta-1,4-diene-3,17-dione
• (6-bromoandrostenedione with additional C1-2 unsaturation)
• 4-chloro-17α-methyl-androsta-1,4-diene-3,17β-diol
• (‘Halodrol’, an Oral Turinabol precursor)
• 4-chloro-17α-methyl-androst-4-ene-3β,17β-diol
• (‘P-Mag’ or ‘Promagnon 25′, a methyl clostebol precursor)
• 4-chloro-17α-methyl-17β-hydroxy-androst-4-en-3-one
• (17a-methyl clostebol)
• 4-chloro-17α-methyl-17β-hydroxy-androst-4-ene-3,11-dione
• (‘Oxyguno’)
• 4-chloro-17α-methyl-androsta-1,4-diene-3,17β-diol
• (‘Halodrol’ again, for some reason)
• 2α,17α-dimethyl-17β-hydroxy-5α-androstan-3-one
• (Methasterone, or ‘Superdrol’. Note that this already appears on the CSA)
• 2α,17α-dimethyl-17β-hydroxy-5β-androstan-3-one
• (An incorrect nomenclature occasionally listed on Superdrol bottles, see here)
• 2α,3α-epithio-17α-methyl-5α-androstan-17β-ol
• (‘Epistane’ or ‘Havoc’)
• [3,2-c]-furazan-5α-androstan-17β-ol
• (‘Furuza’, a non-methylated analogue of Furazabol)
• 3β-hydroxy-estra-4,9,11-trien-17-one
• (Theoretically a precursor to trenbolone; never released and probably never synthesized)
• 17α-methyl-androst-2-ene-3,17β-diol
• (An analogue of desoxymethyltestosterone/madol/phera; never released and probably never synthesized)
• 17α-methyl-androsta-1,4-diene-3,17β-diol
• (M1,4ADD, a precursor to methandrostenolone/Dianabol)
• Estra-4,9,11-triene-3,17-dione
• (‘Trendione’, a trenbolone precursor)
• 18a-Homo-3-hydroxy-estra-2,5(10)-dien-17-one
• (M-LMG without the methoxy group, a precursor to 18-methyl-19-nortestosterone/13-ethylnortestosterone)
• 6α-Methyl-androst-4-ene-3,17-dione
• (An aromatase inhibitor found in ProLine’s ‘Methyl-1 Pro’)
• 17α-Methyl-androstan-3-hydroxyimine-17β-ol
• (‘The One’/’D-Plex’)
• 17α-Methyl-5α-androstan-17β-ol
• (Methylandrostanol; ‘Protobol’)
• 17β-Hydroxy-androstano[2,3-d]isoxazole
• (Androisoxazole)
• 17β-Hydroxy-androstano[3,2-c]isoxazole
• (An isomer of androisoxazole)
• 4-Hydroxy-androst-4-ene-3,17-dione
• (The aromatase inhibitor Formestane)
• [3,2-c]pyrazole-5α-androstan-17β-ol
• (Prostanozol, non-17a-methylated analogue of Stanozolol/Winstrol. Note 1: in the bill they have listed both this compound and formestane in the same subclause (lxxii), as if they were one item. Note 2: This compound already appears on the CSA))
• [3,2-c]pyrazole-androst-4-en-17β-ol
• (A 4,5 unsaturated analogue of the preceding compound)
• [3,2-c]pyrazole-5α-androstan-17β-ol
• (Prostanozol again)

2017年5月7日星期日

How do we reconstitute and inject the growth hormone?



by Alen Hao –Sales Manager of HGH ,Email:alen@ok-biotech.com

Answer:

When in liquid form, the somatropin molecules are very fragile. They easily get destroyed by heat (even room temperatures) and vigorous shaking. Some precautions are necessary - do not inject the water directly into the powder with force, do not drop or shake a reconstituted vial, do not freeze it and do not leave it out of the refrigerator for longer than a few minutes. Keep the freeze dried (lyophilized) growth hormone vials refrigerated as well.

1. Water:

Human growth hormone can be reconstituted with several types of water, including sterile bacteriostatic water (0.9% sodium chloride), normal saline (0.9% NaCl) or plain sterile water for injection. Any will work, but if possible the plain sterile water should be used.

2. Syringes:

Although HGH can be mixed and injected with any type and size of syringe, the Insulin type syringes are the most suitable. If possible get the ones with 100 markings on the side. It will make it easier to properly determine the dosage of HGH.

3. HGH mixing (reconstitution) instruction:

Remove the plastic cap from the top of the vial and clean the rubber with a medical alcohol pad/swab. Take and insulin syringe and pull 1 ml of water (100 markings) into it. Note: regardless of how much water you use (be it 1ml or 2ml) the mixture still has the same overall strength. Water is just a transport method for the HGH. If you used double amount of water when reconstituting the HGH, you would have to use double amount of mixture when injecting yourself to get the same dose. People usually use 1ml because it fits fully into a standard insulin type syringe.

You now have 1ml of water in the syringe. Push the needle through the rubber cap of the vial, but position it sideways so that the water will slide down the inside wall of the vial. Do not inject directly into the powder with force, rather let the water slide out slowly.

Majority of the white powder will dissolve within seconds, but there will be some lumps left over. Do not shake the vial in an attempt to get them to dissolve. If you are in a hurry, you can gently roll the vial between your fingers. If you do this for a few minutes all of the powder will dissolve. Alternatively you can let the vial sit in the refrigerator for 15 - 30 minutes. By that time the somatropin will dissolve completely.

Before pulling the liquid HGH into the insulin syringe, give the vial a few turns between your fingers to gently mix the solution. The HGH vials are under vacuum (negative air pressure) which makes it harder to pull the liquid out. To relieve the vacuum inject a full syringe of air into the top of the vial (do not make the liquid bubble).

Some people use a new syringe for each injection, others pull the entire content of the HGH vial into the syringe and reuse it several times until it's empty. The choice is yours.

4. HGH Dosage:

If somatropin was prescribed to you by a doctor follow his dosage instructions. If you are self prescribing/administering the general dosage guidelines are as follows:

2 IU per day is used for anti aging purposes. You can inject it any time of the day or a full or empty stomach - it does not matter. It might be the most beneficial to take it in the morning, or at least a few hours before bedtime because the body releases its own endogenous growth hormone after a person falls asleep. Injecting before bedtime might reduce the body's own release - robbing you of a free bonus dose.
4 IU per day is usually used by athletes for bodybuilding, fat loss and general fitness. Some people take 6IU per day, however the higher the dose the more annoying the side effects can be. Carpal tunnel syndrome being the side effect which usually forces the athlete to lower the dose or pause the cycle for 2 - 3 weeks until the carpal disappears. It is preferred to spread the daily dose into multiple injections throughout the day. For example 2 IU in the morning and 2 IU in late afternoon.
8 to 16 IU per day is used to speed up recovery after severe burns or injuries. This is a pretty high dose and it should not be continued for more than a few weeks. The carpal tunnel syndrome will probably bother the user, but in the name of faster recovery some discomfort may be tolerable.
Personally tailored, self determined HGH dose

Anything between 2 and 4 IU per day is fine. Each person can determine his body's own preferred dosage. When you get to the carpal tunnel syndrome - that's your limit. For prolonged use it is ok to barely feel the carpal - that's how you know the HGH is working while it doesn't bother you too much. For short periods of time some athletes chose to ignore even the strongly felt syndrome and keep on going until their goals are achieved.

Raised growth hormone levels also make the body use it's thyroid hormone at a heightened pace. While using HGH It is a good idea to periodically check all your hormone levels to make sure everything is ok. If the thyroid levels are too low it might be time to lower the HGH dosage or pause the cycle for a while.

Warning: HGH has a direct effect on a person's blood sugar levels. If you have diabetes you might want to consult a professional before self administering growth hormone. While taking HGH your insulin levels might have to be adjusted. There would be a few days period of instability when first starting HGH, modifying the dosage or ending the HGH cycle. Diabetes patients might want to gradually build up to the desired HGH dose and at the end of the cycle also take 2-3 weeks to gradually phase out the HGH injections.

5. HGH injections:

Growth hormone can be injected intramuscularly (IM) into pretty much any muscle or subcutaneously (SQ) - under the skin in the stomach fat area. Injections above the belly button are usually less painful than the ones below the belly button. A different spot should be used for each injection (to avoid potentially producing dents in the body fat - as hgh is believed to promote localized fat reduction).

For SQ injections pinch the skin between your abs, fully insert the needle at a 30 - 45 degrees angle and inject your dose. For IM injections fully insert the needle into your shoulder or gluteus muscle and release the dose.

It is rumored that the SQ injections produce better effect due to the fact that HGH is more readily available from there. Personally I see no difference whether I inject IM or SQ. Injecting HGH intramuscularly is less unpleasant for me, so that's how I do it.

6. Starting or ending the HGH cycle

There are various internet forum misconceptions about the proper use of growth hormone. Some date back to the beginning of the internet and are still being repeated by people who "heard from a friend".

Some people think that growth hormone should be taken 5 days per week with 2 days pause in between. This is nonsense which only came about because back in the days HGH was prohibitively expensive and bodybuilders prolonged their cycles by skipping days and stretching it for as long as they could afford. The human body never pauses the production of it's endogenous growth hormone.

Some people believe that in beginning of the growth hormone cycle the desired dosage should be gradually built to and gradually phased out when the person is ready to end it. From my experience it makes no difference whether I phase in and out or start and stop with full dosage. On the other hand, I do get a few days of blood sugar instability (sudden hypoglycaemia) when I end my cycles. Within 2 days to 2 weeks after my cycle is complete I get sudden hunger attacks (blood sugar drops). I keep a candy bar handy for such episodes. It happens about 3 to 5 times in the 2 weeks period.

2017年5月4日星期四

Post Cycle Therapy



PCT)

Post Cycle Therapy or PCT is a period of medication treatment that follows the use of anabolic steroids. Post Cycle Therapy is also one of the most confusing topics for many steroid users; this is largely due to misconceptions. When to start PCT, which meds to use, how long to use them and what you should expect, these are all common questions and ones we’ll address here.

The Purpose of PCT
When we supplement with anabolic steroids we suppress our natural testosterone production. Testosterone, the primary male hormone, is essential to our very well being. Most men who supplement with anabolic steroids will always include at least a minimal amount of testosterone in their cycle due to this suppression factor.

Testosterone is manufactured in the testicles. For testosterone to exist the pituitary releases two gonadotropins Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FHS); this tells the testicles to make testosterone. When we take anabolic steroids the signal that tells the pituitary to produce LH and FSH is reduced and therefore less testosterone is produced. If we are supplementing with testosterone this suppression is of very little consequence as we’re providing our body with what it needs through an outside source. However, once the steroid use comes to an end we have the issue of a suppressed signal that must be dealt with. That is the purpose of PCT, to stimulate natural testosterone production so that we are not left in a low testosterone state.

D-Anabol 25

The Suppression Myth
It’s often said that if you take any anabolic steroid you now produce no testosterone but this isn’t exactly true. All anabolic steroids will suppress natural testosterone production, but the rate of suppression is dependent on the steroids. A steroid like Nandrolone (Deca Durabolin) will result in 100% suppression of natural production after a single 100mg dose. However, a steroid like Oxandrolone (Anavar) will not result in full suppression. With milder steroids like Anavar how much suppression exists will be dependent on dose, duration of use and genetics. However, even though suppression may not be 100% it will still be enough in every case for there to be a need for testosterone supplementation during use. Even if a steroid does not cause full suppression it will be enough to put your testosterone into a low level state.

Important Note: the need for testosterone supplementation during anabolic steroid use does not apply to women nor does the need for PCT.

What to Expect from PCT

The biggest problem with most PCT plans is the individual having unrealistic explanations. Most PCT plans will last 4-6 weeks and many men expect everything to be back to normal once this 4-6 week period is complete. PCT does not work this way. Many men also expect for all their gains be they weight or strength gains to be maintained post-PCT if the PCT plan was proper and appropriate. Again, PCT does not work this way.

A good PCT plan will help you protect and maintain some of the progress you made, but if the high influx of hormones is no longer there (the high influx of hormones that helped you make your gains), without that support system you will lose some of your gains. A good way to look at is as we look at food – the nutrients you eat help you buildup your body. The nutrients you eat become the support system. Take away the nutrients and the support system goes away with it and the “Building” begins to collapse. For this reason it’s not uncommon for some men to begin consuming extra calories during PCT in order to protect their gains – in simplistic terms they’re substituting in nutrients for the hormones that have been taken away. This can help maintain weight but it’s not always a good idea. Weight is just weight and if it’s not weight that’s muscle tissue it’s rather useless. It’s not uncommon for some men to put on a good bit of body fat during this phase due to their desperation to hang onto gains.

The primary purpose of PCT is to stimulate natural testosterone production. Some gains may be lost during this period, but it’s not the end of the world. For the steroid user he will be on cycle again one day. For the present period he should focus on his hormone recovery, continue to train and eat properly protecting the gains he can without putting on excess body fat. This is truly the only logical long-term approach.

When NOT to Run PCT

If you’re a hardcore steroid user, meaning you’re on cycle more than you’re off, running a PCT can be counter productive. For example, a man completes a cycle, implements PCT and then jumps back on cycle right after or soon after PCT. This is a very harsh practice and terrible for your body. You are shutting down your natural testosterone production, stimulating it through PCT and then shutting it right back down. You’ve put yourself on a never ending rollercoaster with your hormone levels that’s going to wreak havoc on your body. For such an individual he would be better off running a low dose of testosterone, therapeutic levels, during his time between cycles. This is not an approach most men should take. Most men who use steroids need to come off and stay off after PCT is complete for a time if long-term health is important to them.

Another time not to run PCT is if you are a low testosterone patient. A low testosterone patient has no natural ability to produce enough testosterone on his own, which is why he needs testosterone supplementation. If he happens to implement a cycle at some point during his treatment, once the cycle is over he should simply continue on with his previous Testosterone Replacement Therapy (TRT). If you implement a PCT plan you’re only attempting to stimulate what is naturally a low level, and it will serve no purpose.

PCT Medications

There are many medications that can be theoretically used for PCT but only two that should be primary, Tamoxifen (Nolvadex) and Clomiphene (Clomid). Both Nolvadex and Clomid fall in the class of drugs known as Selective Estrogen Receptor Modulators (SERMs). As with all SERMs ‘Nolva’ and Clomid stimulate the release of LH and FSH thereby increasing natural testosterone production. For most PCT plans these will be the only two medications needed.

HCG (Human Chorionic Gonadatropin) is also sometimes used during the PCT phase. When supplementing with testosterone, especially in modern times, many men include low doses of HCG in their steroid cycles, normally 250-350iu a couple times per week. HCG mimics LH and therefore actually keeps the testicles producing testosterone even when anabolic steroids are present. However, it does not induce the production of actual LH. The use of HCG on cycle, this is primarily done so that post cycle recovery is easier (theoretically). HCG is also used on cycle to prevent or at least minimize testicular atrophy that occurs due to the use of anabolic steroids. The testicular atrophy that occurs is not permanent but will reverse once steroid use is discontinued and natural testosterone production begins again.

If HCG is used on cycle there is no need to use it post cycle. However, some men will not use HCG during their cycle for a variety of reasons. Although it is not extremely common, HCG use can increase estradiol levels significantly in some men even with the use of an Aromatase Inhibitor (AI). AI’s are regularly used to combat estrogenic issues during a cycle, but it’s generally best to keep them as minimal as possible. If HCG is not used on cycle it may be the preamble to the PCT plan in some cases. We’ll go over this more later.

AI’s are also sometimes used during PCT because of their ability to stimulate LH and FSH. However, they also lower estrogen levels and often too much during this phase. Part of the PCT plan is to allow the body to normalize and part of that is maintaining normal estrogen levels. Estrogen is not an evil hormone many men, especially steroid users often believe it is. Estrogen is extremely important for muscle building, sexual health, mental health and a host of other areas. Estrogen levels that are too high or too low, both can be very problematic.

When to Start PCT

Timing is a very important factor when it comes to PCT. If all short ester base steroids are used, such as Testosterone Propionate, Trenbolone Acetate, etc. PCT should begin 3-4 days after your last injection. However, if any long or large ester base steroids are used, such as Testosterone Cypionate, Nandrolone Decanoate, etc. you’ll want to wait at least 14 days before beginning PCT. If Nandrolone Decanoate is used it may not be a bad idea to wait a full 21 days before beginning PCT.

If HCG is used as part of the PCT plan (generally not recommended if used on cycle) if all short ester base steroids are used HCG use will begin approximately 3 days after your last injection and last for 10 days of treatment. If any large ester base steroids are used HCG will begin approximately 10 days after your last injection and last for 10 days of treatment. In either case, once HCG use is complete the use of SERMs will immediately begin.

SERM Plan

Both Nolvadex and Clomid stimulate LH and FSH, but Nolvadex does more for LH and Clomid more of FSH. A solid PCT plan will generally include both SERMs. 4-6 weeks of treatment is normally sufficient. A good plan to follow would be 100mg of Clomid per day for two weeks with 40mg of Nolvadex per day for Two weeks. This will be followed by 50mg of Clomid per day for two weeks and 20mg of Nolvadex per day for two weeks. An additional two weeks of Nolvadex at 20mg per day may be added if needed.

Week 1-2: Clomid 100mg per day

Week 1-2: Nolvadex 40mg per day

Week 3-4: Clomid 50mg per day

Week 3-4: Nolvadex 20mg per day

(Optional) Week 5-6: Nolvadex 20mg per day

When to Start Your Next Cycle

For optimal health the general rule to follow is time on equals time off. If your cycle last 10 weeks and your PCT plan last 4 weeks you will wait 14 weeks before starting a new cycle. A mistake many men make is saying testosterone levels have recovered and it is now Okay to start a new cycle. If you do this you have not allowed your body time to normalize.
Post Cycle Therapy
Blood Work

It’s always a good idea to get blood work done after PCT to see where your body is at; however, this won’t be the full story. When we run a PCT we are artificially stimulating natural testosterone production – the stimulation would not exist without the implementation of SERMs. The true tale of the tape is where your numbers are after a good bit of time has passed; say several months.

The Most Common Myth

It can take several months for you testosterone levels to recover and hold post steroid use and post PCT. The common myth some hold to is that once PCT is complete and levels are up this means everything is good to go. As we discussed above, true recovery means your levels can hold without any type of supplementation, if not then full recovery has not been reached.

The Danger

If you’re going to supplement with anabolic steroids there is one single truth you need to understand, risks exists. One of these risks is permanently lowering your natural testosterone production and forever being in need of TRT. Even with the best PCT plan in the world this risk exists. The point of PCT is to help and minimize this risk; it does not completely remove it. If this is something you cannot accept then anabolic steroid use is not for you.

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2017年5月2日星期二

Clenbuterol Cycle


There are many ways to plan a Clenbuterol cycle with three being the far most common with two being the most effective; yes, of these two there is one that is truly best. For a Clenbuterol cycle the options will generally be, 2 days on/2 days off, 2 weeks on/2 weeks off and continuous use with incrementing dosing throughout. We will discuss all three methods and in the end you can choose which is best for you but understand, regardless of what you decide there can only be one king; meaning only one method is truly 100% efficient.
Bursting Clenbuterol Cycle:
The 2 day on/2 day off method we may aptly call a bursting Clenbuterol cycle as that is exactly what the individual is doing by way of this method. The idea is simple; blast for 2 days with a relatively high dose and follow with nothing for 2 days and then repeat. Such use is often used for extended periods of time, even months and of the three methods we find this to be by far the most ineffective and strenuous to the body. Such a method causes a lot of undue stress and a lot of up and down activity within the body. Further, this method does not make full use of the fat-burning potential of this Beta-2 stimulator. By and large of the various forms this particular Clenbuterol cycle while it will provide results is our least favorite.

The Most Common Clenbuterol Cycle:
For years the 2 week on/2 week off Clenbuterol cycle has been the most popular among performance enhancers largely thanks to internet message boards. This is a very effective means of supplementing with this medication for fat-burning, far more so than the bursting method discussed above. Generally speaking this type of Clenbuterol cycle is very simple and begins with a low dose normally in the 20mcg-40mcg range. The individual will increase the dose every day or two until he reaches the maximum desired dose that normally falls in the 100mcg-140mcg range and then discontinue use at the 2 week mark. At this point 2 more weeks will follow with no Clenbuterol in the system and at the end of this break use will begin again, normally at the ending dose of the last run; for example, if the first 2 weeks ended with 100mcg the next course of use will begin at 100mcg. Normally the individual will hold at this dose and continue with the 2 week on/2 week off method starting with the maximum desired dose each 2 week on period after the initial 2 week period.

Clen
Incrementing Clenbuterol Cycle:
While not as popular as the 2 week on/2 week off method the incrementing Clenbuterol cycle has been fast gaining popularity over recent years and for good reason; it makes the most sense and is by far the most efficient as well as effective. The plan is very simple; starting at a low dose, generally in the 20mcg-40mcg range the individual will increase the dose 20mcg every 2-3 weeks as needed. This method allows for Clenbuterol to be used for the full extent of the diet thereby keeping the metabolism revved up through the course of the total duration.

The Common Concern:
The reason many opt for the 2 week on/2 week off Clenbuterol cycle is simple; the body adapts to the medication and by taking a break from use you are able to maintain a positive metabolic output each and every time use begins. However, this method has a problem, for when use is discontinued the metabolism slows down due to the absence of the fat-burner that heats up your body temperature; without its presence the body temperature drops due to the mitochondria now producing less heat and the metabolism slows down. Through the incremental Clenbuterol cycle this is not a problem because the medication remains in the system through the duration of the dieting phase; but what about your bodys adaptation? By slowly and steadily incrementing the dose upwards every 2-3 weeks you do not allow your body to become accustomed; it is true, the jittery feeling often associated with this bronchodilator may be less but jittery or not has nothing to do with the medication working.

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2017年5月1日星期一

Masteron (drostanolone propionate)



(Drostanolone Propionate)

by Alen Hao –Sales Manager of Raw steroid powder ,Email:alen@ok-biotech.com

Drostanolone Propionate is an anabolic androgenic steroid that first hit the market around 1970 under the trade name Masteron manufactured by Syntex. However, the compound was actually developed by Syntex in 1959 along with Oxymetholone (Anadrol) but would not be released until well after Anadrol. Syntex would also provide the compound under numerous other brand names such as Masteril and Metormon among others, as well as Drolban under the license given by Syntext to Lilly. However, Masteron has remained the most recognizable brand.

Test 600x  As a therapeutic agent, Masteron enjoyed two decades of success in combating advanced inoperable breast cancer in postmenopausal women. It would also become a popular cutting steroid among bodybuilders, which is where Masteron is currently most commonly found. However, the original Masteron brand is no longer available; in fact, nearly every pharmaceutical brand on earth has been discontinued. This compound is still approved by the U.S. FDA, but it is rarely used in breast cancer treatment any longer in favor of other options. The steroid is, however, still tremendously popular in competitive bodybuilding cycles and often considered essential to contest preparation.

Masteron Functions & Traits:
Drostanolone Propionate is a dihydrotestosterone (DHT) derived anabolic steroid. Specifically, Masteron is the DHT hormone that has been structurally altered by the addition of a methyl group at the carbon 2 position, This protects the hormone from the metabolic breakdown by the 3-hydroxysteroid dehydrogenase enzyme, which is found in the skeletal muscle. It also greatly increases the hormone’s anabolic nature. This simple structural change is all it takes to create Drostanolone, and from here the small/short Propionate ester is attached in order to control the hormone’s release time. Drostanolone Enanthate can also be found through some underground labs, which does not have to be injected as frequently, but it is somewhat rare compared to the Propionate version. The majority of all Masteron on the market will be Drostanolone Propionate.

On a functional basis, Masteron is well-known for being one of the only anabolic steroids with strong anti-estrogenic properties. Not only does this steroid carry no estrogenic activity, but it can actually act as an anti-estrogen in the body. This is why it has been effective in the treatment of breast cancer. In fact, the combination of Masteron and Nolvadex (Tamoxifen Citrate) has been shown to be far more effective than chemotherapy in the treatment of inoperable breast cancer in postmenopausal women. This also makes it a popular steroid among bodybuilders as it could actually prohibit the need for an anti-estrogen when used in the right cycle. This will also prove advantageous during the cutting phase due to the hardening effects it can provide.

Masteron carries relatively low anabolic and androgenic ratings; however, these ratings are somewhat misleading. It’s important to remember DHT, the basis of Masteron, is five times more androgenic than testosterone with a much stronger binding affinity to the androgen receptor. This again promotes a harder look and can also enhance fat loss. Most all anabolic steroids are well-noted for enhancing the metabolic rate, but strong androgens have a tendency to directly promote lipolysis.

As an anabolic, Masteron isn’t well-known for promoting gains in lean muscle mass. It has never been used for muscle wasting in a therapeutic sense and will almost always be found in cutting plans among performance athletes. It can, however, promote significant boosts in strength, which could prove beneficial to an athlete who may not necessarily be looking for raw mass.

Effects of Masteron:
Without question, the effects of Masteron will be displayed in the most efficient way during a cutting cycle. However, for the effects to be truly appreciated the individual will need to be extremely lean. This is why the hormone will most commonly be found at the end of bodybuilding contest prep cycles as the individual should already be fairly lean at this stage. The added Masteron will help him lose that last bit of fat that often hangs on for dear life at the end of a cycle. It will also ensure his physique appears as hard as can be. Of course, the anti-estrogenic effect will simply enhance this overall look. For those that are not competitive bodybuilder lean, it is possible that the effects of Masteron may not be all that noticeable. The individual who is under 10% body fat should be able to notice some results and produce a harder, dryer look, but much over 10% and the effects may not be all that pronounced.

As a potent androgen, Masteron can benefit the athlete looking for a boost in strength. This can be a very beneficial steroid for an athlete who is following a calorie restricted diet in an effort to maintain a specific bodyweight necessary for his pursuit. The individual could easily enjoy moderate increases in strength and a slight improvement in recovery and muscular endurance without unwanted body weight gain.


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As a bulking agent, the effects of Masteron will prove to be rather week. It is possible the hormone could provide gains in mass similar to Primobolan Depot, which won’t be that strong either, if the total dose was high enough. However, the relative gain in size will be very moderate with many anabolic steroids being far more suited for this period of steroidal supplementation. There are those who may wish to include Masteron in a bulking plan for its anti-estrogenic and fat loss effects. The latter would ensure they kept their body fat gain minimized during off-season bulking phases, but this isn’t reason enough to use it in this phase. Body fat should be controllable without it. As for the anti-estrogenic effects, off-season cycles are normally comprised of large amounts of aromatase activity due to high doses of testosterone. Progesterone activity is also commonly high with the addition of Nandrolone compounds and possible Trenbolone. Consider additional Anadrol or Dianabol and this estrogenic activity can become very pronounced. Unfortunately, while possessing anti-estrogenic effects, Masteron will not be strong enough to combat this level of estrogenic activity.

Side Effects of Masteron:
In many ways, Masteron is a fairly side effect friendly anabolic steroid. Side effects of Masteron use most certainly exist, but most men will find this steroid highly tolerable. As for females, virilization symptoms can be strong with this steroid, but we will also find they can be managed with the right plan. In order to understand the side effects of Masteron, we have broken them down into their separate categories along with all you need to know.

Estrogenic:

Masteron does not aromatize and it does not carry any progestin nature making estrogenic side effects impossible with this steroid. This means gynecomastia and water retention will not be concerns. It also means high blood pressure that is sometimes caused by excess water retention will not be a concern. An anti-estrogen is not needed due to this steroid’s use; as discussed it can have anti-estrogenic effects itself. However, depending on the specific cycle/stack that’s implemented, an anti-estrogen may be needed.


Androgenic:

The side effects of Masteron can include those of an androgenic nature. Androgenic side effects can include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. Thankfully this hormone carries a moderate level of total androgenic activity despite being a direct derivative of the potent androgen DHT. However, individual sensitivity will play a strong role, this steroid is well-known for greatly enhancing male pattern baldness in sensitive men far more than many anabolic steroids.

An important note; the Drostanolone hormone is not metabolized by the 5-alpha reductase enzyme. This is the enzyme responsible for reducing testosterone to dihydrotestosterone. In the case of Masteron, it’s already DHT; there is no reduction. As there is no reduction, there is no metabolism and nothing to inhibit. This means the androgenic nature of Masteron will not be strongly affected by a 5-alpha reductase inhibitor such as Finasteride.

Due to its androgenic nature, Masteron can produce virilization symptoms in women. Virilization symptoms can include body hair growth, a deepening of the vocal chords and clitoral enlargement. Virilization symptoms have been well-noted in breast cancer treatment plans, but this is normally due to the necessary high doses used to treat such a condition. In a performance capacity, it should be possible to use this steroid without related symptoms with a low dose. However, while individual response will dictate quite a bit, this will not be a primary recommended steroid for female athletes. If it is used and related symptoms begin to show, discontinue use immediately and they will fade away. If the symptoms are ignored, it is very possible they may set in and become irreversible.


Cardiovascular:

Masteron can have a significant effect on cholesterol. This can result in an increase in LDL cholesterol, as well as a decrease in HDL cholesterol with the strongest emphasis on the latter. The total affect on cholesterol will not be as strong as often found in many oral steroids, specifically C17-alpha alkylated steroids. However, the total affect on cholesterol management will be stronger than compared to Nandrolone compounds or the testosterone hormone. It is also possible that Masteron could have a slight negative impact on blood pressure, but this will be a non-issue for most.

Due to the cholesterol effects of Drostanolone, cholesterol management becomes very important with this steroid. Far more important than with basic testosterone cycles or stacks including a basic 19-nor. If you already suffer from high cholesterol you should not use this anabolic steroid. If you are healthy enough for use, maintaining a cholesterol friendly lifestyle is very important. Not only does this mean a healthy diet, but it should be one that includes plenty of omega fatty acids, is limited in saturated fats as well as simple sugars. Plenty of cardiovascular activity is also advised.


Testosterone:

Masteron will significantly suppress natural testosterone production making exogenous testosterone therapy important when using this steroid. Failure to include exogenous testosterone will lead most men to a low testosterone condition, which not only comes with numerous possible symptoms but is also extremely unhealthy.

As most will use Masteron in a cutting cycle, it’s very common not to want to use a lot of testosterone due to the high levels of estrogenic activity it can provide. If this is the case, you will find a low dose of 100-200mg per week of testosterone to be enough to combat suppression and give you the needed testosterone.

Once Masteron is discontinued and all exogenous steroidal hormones have cleared your system, natural testosterone production will begin again. Prior levels will not return to normal over night, this will take several months. Due to the slow recovery, Post Cycle Therapy (PCT) plans are often recommended. This will speed up the recovery greatly; however, it won’t bring your levels back to their peak, this will still take time. A PCT plan will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise and significantly cut down on the total recovery time. This natural recovery does assume no prior low testosterone condition existed. It also assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) through improper supplementation practices.


Hepatotoxicity:

Masteron is not a hepatotoxic anabolic androgenic steroid and will present no stress or damage to the liver.

Masteron Administration:
The standard Masteron dose for adult men will normally fall in the 300-400mg per week range. Normally, this will mean an injection of 100mg every other day for a total of 6-8 weeks. This does not mean 6-8 weeks represents the total cycle, but this is a common time frame for the Masteron portion of a stack. Some may alternatively choose to split their dose up into a daily injection schedule, but every other day should suffice. If a Drostanolone Enanthate version is found, 1-2 injections per week will work, but such a version is somewhat rare.

For female breast cancer treatment, standard dosing calls for 100mg three times per weeks for 8-12 weeks. This will commonly lead to virilization symptoms that could be hard to reverse. However, no one can deny it’s still better than cancer. For the female athlete, 50mg per week should be more than enough for a total of 4-6 weeks. Some women may find doses closer to 100mg per week to be justified if they tolerate the hormone well. Doses of this range should be controllable for most women, but individual sensitivity must be kept in mind. Doses that go above the 100mg per week mark or beyond 4-6 weeks of use will more than likely produce virilization symptoms at some level.

Availability of Masteron:
The original Masteron brand of Drostanolone Propionate is no longer manufactured. Anyone purporting to have Syntex Masteron is providing a counterfeit product. There is further no U.S. pharmaceutical company that manufactures Drostanolone in any form, and it is very scarce on the world market. However, this hormonal compound is widely available on the black market. The Mastabolin brand by Alpha Pharma should be in high supply in most markets. Underground labs like Geneza, Biomex, QD Labs and Generic Labs are all big suppliers of the compound. When dealing with any underground lab, it is extremely important that you research the lab and supplier in question before making a purchase. Regardless of the lab in question, you should find Masteron to be fairly affordable in the current market. This is a bonus as not long ago it was a fairly expensive anabolic steroid.

Buy Masteron Online - Warning:
If you decide to buy Masteron online, you will find this is the easiest and most affordable way to purchase the product. There are seemingly countless large suppliers of anabolic steroids online, but unfortunately, they are not all created equally. Being scammed out of your money, purchasing a low dosed or counterfeit product or a contaminated one are all possibilities. This makes researching your supplier beyond imperative. Just because someone is offering to sell you Masteron doesn’t mean you should buy it. There are several quality suppliers online, but understand there are probably more low grade suppliers than not.

If you buy Masteron online, there is also the legal risk that cannot be ignored. In the United States anabolic androgenic steroids are classified as Schedule III controlled substances. If you buy Masteron online or through a face-to-face transaction, you will be breaking the law, and it can come with horrific consequences. The steroid laws of varying countries can differ greatly, some are similarly strict to the U.S. while others are far more lenient; however, most frown heavily on online purchases. For this reason, if you are looking for high quality anabolics without fear of legal consequences, you are encouraged to visit the sponsors here at Steroid.com. The sponsors here at Steroid.com can provide you legal anabolics of a high quality nature without a prescription or fear of legal reprisal.

Masteron Reviews:
In some performance enhancing circles, Masteron is viewed as a relatively weak anabolic steroid. This is largely due to the steroid having low mass promotion abilities, and many tend to equate quality steroids to their mass promotion characteristics. Some also tend to forget that while a steroid may be a quality one, it will not present notable benefits unless you are very lean. This tends to lead many to having a skewed perception of Masteron due to this improper thinking. This is a very valuable anabolic steroid, but you must understand the purpose of use and the benefits it can provide if such beneficial rewards are going to be gained. Understand that raw mass promotion is not the end all be all of progress; understand the total purpose of use of a steroid and when to use it and you will find Masteron to be a very valuable anabolic steroid.

Masteron Profile:
(Drostanolone Propionate)
[17beta-Hydroxy-2alpha-methyl-5alpha-androstan-3-one propionate]
Molecular Weight: 360.5356
Formula: C23H36O3
Melting Point: N/A
Manufacturer: Syntex (originally), Various Underground Labs
Effective Dose (men): 350mgs/week (*100mgs Every other day) to 500mgs/week
Effective Dose (women): 50-100mg/week
Active Life:2-3 days
Detection time: 3 weeks
Anabolic/Androgenic Ratio: 62:25